Cheongdam Dermatology | What are the differences between Re2O cannula injections and traditional injections in terms of technique and pain?
2026-11-12
Contents
What is Re2O cannula injection?
The Re2O procedure is performed by medical professionals who directly manipulate the syringe to inject the medication. Depending on the tool used, it can be categorized into traditional injections using a regular needle and procedures using a cannula.
Traditional injections using a regular needle involve inserting a sharp and pointed tip directly into the skin to inject the medication.
In contrast, a cannula has a rounded and blunt tip, which is inserted after creating a small entry point in the skin to deliver the medication beneath the skin.

Both methods involve medical professionals directly manipulating the syringe for the procedure. This means that it is not the act of the medical professional that changes, but rather the tool used to deliver the medication. This difference can lead to variations in how the skin is accessed and how the medication is delivered.
What are the differences between Re2O cannula and traditional injections?
The most significant difference lies in the shape of the injection tool and the method of insertion into the skin.
The cannula can be inserted through a small entry point made in the skin and can move beneath the skin to inject the medication. In contrast, traditional injections involve directly inserting the needle into the required area to deliver the medication.
When comparing the characteristics of both methods, they can be summarized as follows:
Comparison Item | Cannula | Traditional Injection |
|---|---|---|
Tool Used | Rounded and blunt-tipped cannula | Sharp and pointed regular needle |
Insertion Method | Inserted after creating a small entry point in the skin | Directly inserted into the skin |
Medication Delivery | Injects medication while moving beneath the skin | Directly injects medication into the area where the needle is inserted |
Injection Range | Can be used to deliver medication over a wide area | Can be used to deliver medication to specific points |
Main Features | Can access multiple surrounding areas through one entry point | Insertion points and frequency may vary depending on the injection site |
The cannula has the characteristic of moving beneath the skin while pushing surrounding tissues aside due to its rounded and blunt tip. However, the actual reactions that occur during the procedure can vary depending on the injection site and individual conditions.
Traditional injections have the advantage of directly accessing the desired point to deliver the medication.

Therefore, it cannot be said that one tool is always more suitable than the other. The choice should be made considering the area and range that require injection, as well as the skin condition.
Are there differences in pain or bruising between Re2O cannula and traditional injections?
Since the process and frequency of insertion into the skin can vary depending on the tool used, there may also be differences in the sensations experienced during the procedure and the reactions that occur afterward.
The cannula delivers medication while moving beneath the skin through a small entry point. Compared to the method of repeatedly inserting the needle at multiple points when injecting a wide area, the number of entry points and the pattern of tissue stimulation may differ.
On the other hand, traditional injections involve directly inserting the needle into the required points. Therefore, the appearance of injection marks or sensations of stimulation may also vary depending on the injection site and the number of insertions.
Pain and bruising are not determined solely by the differences in tools. Various factors such as individual pain sensitivity, skin condition, injection site, depth of injection, and the process itself all play a role. Using a cannula does not necessarily mean that pain or bruising will be reduced, and there can be individual differences in discomfort experienced during the procedure.
If you are concerned about pain, it is advisable to consider not only the tools used but also what methods can be employed during the procedure to minimize discomfort.
What should be considered before Re2O cannula injection?
Before selecting the injection tool, it is essential to first assess the injection area, skin condition, and treatment goals.
For example, whether medication needs to be delivered over a wide area or directly injected into specific points can influence the choice of tool. The thickness of the skin and the characteristics of different areas, as well as the range of injection needed, should also be considered.
Based on these factors, the appropriate tool between a cannula and a regular needle will be reviewed. It is important to consider an approach that fits the treatment area and goals rather than simply preferring one tool over the other.
The actual tools and injection processes used can vary depending on the individual's skin condition, treatment area, and management goals.
How does AMRED consider the Re2O injection method?
At AMRED, when planning the Re2O procedure, it is important to assess the individual's skin condition and treatment goals, and to consult on the appropriate treatment direction.
Since cannulas and traditional needles differ in shape and insertion methods, it is necessary to review the appropriate tools considering the treatment area and injection range. It is also advisable to have a thorough understanding of not only which tool is used but also the expected procedure and any discomfort that may arise.

Especially if there are concerns about pain or preferred treatment methods, it is important to discuss these thoroughly with the medical professionals in advance. Based on this, it is essential to explore the direction that aligns with the skin condition and treatment goals.
The Re2O injection method should be understood not just by comparing the tools used but also by considering the characteristics of each tool and the specifics of the treatment area. Through sufficient consultation, you can find the treatment method that is suitable for you.